Software Development AI agent skills

13,359 skills in the archive. Read a skill’s instructions or open its original repository.

• Gi Enhancer

  by @ClawBio

  Predict enhancer activity in DNA sequences using the Genomic Intelligence G0 DeepSTARR model, via the hosted /v1/tasks/enhancer/predict API. Returns per-window activity scores.

• Fastreer

  by @ClawBio

  Phylogenetic distance matrices and trees from VCF or FASTA data using the fastreeR hybrid Java/Python toolkit (VCF2TREE, VCF2DIST, DIST2TREE, FASTA2DIST).

• Variant Annotation

  by @ClawBio

  Annotate VCF variants with Ensembl VEP REST, ClinVar significance, gnomAD/population frequency context, and prioritized variant ranking.

• Methylation Clock

  by @ClawBio

  Compute epigenetic age from DNA methylation arrays using PyAging clocks from GEO accessions or local files.

• Matlab Connect Databricks

  by @matlab

  Connect MATLAB to Databricks via Spark (Databricks Connect) or JDBC (Database Toolbox). Use when setting up the MATLAB Interface for Databricks, configuring authentication (OauthU2M, OauthM2M, PAT), creating Spark sessions with…

• Matlab Optimize Gpu Codegen

  by @matlab

  Optimize MATLAB design files for GPU Coder to generate faster CUDA code. Iteratively profiles, rewrites, and benchmarks until performance targets are met or diagnostics are resolved. Use when asked to: optimize for GPU Coder,…

• Mendelian Randomisation

  by @ClawBio

  Two-sample Mendelian Randomisation from GWAS summary statistics with IVW, MR-Egger, weighted median/mode, and full sensitivity analysis (Cochran Q, Egger intercept, Steiger, F-statistic, leave-one-out).

• Bioconductor Bridge

  by @ClawBio

  Bioconductor package discovery, workflow recommendation, setup inspection, and starter code generation grounded in official Bioconductor containers and BiocManager.

• Flow Bio

  by @ClawBio

  Flow.bio API bridge — authenticate, browse pipelines/samples/projects, search, upload data, launch pipeline executions, and check run status on any Flow instance.

• Organ Aging Studio

  by @ClawBio

  Interactive Goeminne proteomic aging clock with organ filters and per-protein contribution breakdown (protein NPX × coefficient). Agent- and demo-friendly.

• Skill Builder

  by @ClawBio

  Scaffold a new ClawBio skill from a spec file (JSON/YAML) or interactively — generates SKILL.md, Python skeleton, tests, and updates catalog.json

• Rnaseq De

  by @ClawBio

  Differential expression analysis for bulk RNA-seq and pseudo-bulk count matrices with QC, PCA, and contrast testing.

• Matlab Upgrade Mex Ic

  by @matlab

  Upgrade C, C++, and Fortran MEX source files from the Separate Complex (SC) API to the Interleaved Complex (IC) API. Use when converting mxGetPr/mxGetPi to mxGetComplexDoubles, migrating MEX files to -R2018a, adding…

• Clinical Variant Prioritizer

  by @ClawBio

  Screen a genotype set (array or WGS-derived) against OMIM-morbid, ACMG-SF and Hereditary-Cancer gene panels and prioritise carried variants by ClinVar significance, gnomAD frequency, inheritance model and zygosity, following the…

• Cell Detection

  by @ClawBio

  Cell segmentation in fluorescence microscopy images. Supports Cellpose/cpsam (Cellpose 4.0) with additional backends planned. Produces segmentation masks, per-cell morphology metrics (area, diameter, centroid, eccentricity),…

• Multiqc Reporter

  by @ClawBio

  Aggregates QC reports from any bioinformatics tool outputs (FastQC, fastp, STAR, Picard, samtools, etc.) into a single MultiQC HTML report plus a ClawBio markdown summary with per-sample QC metrics.

• Vcf Annotator

  by @ClawBio

  Annotate VCF variants with Ensembl VEP, ClinVar, and gnomAD. Ranks variants by impact (HIGH/MODERATE/LOW/MODIFIER) and generates a reproducible report.

• Sample Qc Triage

  by @ClawBio

  Deterministic multi-sample QC triage for identity, sex, contamination, and batch-shift outliers

• Crispr Screen Triage

  by @ClawBio

  Deterministic CRISPR screen hit ranking from local guide-level count tables

• Marker Dominance Mapper

  by @ClawBio

  Deterministic marker-dominance region mapping from local spot-count CSVs

• Matlab Call Python

  by @matlab

  Call Python libraries from MATLAB using the py. interface, pyrun, pyrunfile, or pyenv. Use when writing or executing MATLAB code that calls Python functions or passes data between MATLAB and Python. REQUIRED when triaging Python…

• Matlab Instrument Opentelemetry Tracing

  by @matlab

  Add OpenTelemetry tracing to MATLAB code. Use when the user asks to "add tracing", "instrument with spans", "add OpenTelemetry", "trace my code", "add observability" (when about tracing), or mentions "spans", "distributed…

• Matlab Install Products

  by @matlab

  Deterministic workflow to download MATLAB Package Manager (mpm) and install MathWorks products from the OS command line with consistent, repeatable behavior. Use when installing MATLAB, Simulink, toolboxes, or support packages…

• Scrna Orchestrator

  by @ClawBio

  Local Scanpy pipeline for single-cell RNA-seq QC, optional doublet detection, clustering, marker discovery, optional CellTypist annotation, optional latent downstream mode from integrated.h5ad/X_scvi, and optional dataset-level…

• Matlab Optimize Memory

  by @matlab

  Guides the 7-step MATLAB memory optimization workflow: baseline, profile, identify, optimize, measure, verify, report. Use when asked to reduce MATLAB memory usage, find memory bottlenecks, fix out-of-memory errors, or optimize…

• Matlab Set Up Worker State

  by @matlab

  Set up worker environment and per-worker state for parallel pools. Use when code needs paths, environment variables, database connections, loaded libraries, or expensive objects available on workers before parfor/parfeval runs.…

• Matlab Secure Credentials

  by @matlab

  Store, retrieve, and pass credentials securely in MATLAB using the built-in MATLAB Vault (setSecret, getSecret, importSecrets, secretID) instead of hardcoding. Handles connections to any authenticated service: REST APIs,…

• Matlab Cosimulate Sumo Simulink

  by @matlab

  Build Simulink models that co-simulate with Eclipse SUMO traffic simulator. Use when creating SUMO-Simulink co-simulation, traffic simulation, TraCI connection, vehicle-in-the-loop testing, or ADAS scenario validation with SUMO.…

• Matlab Review Code

  by @matlab

  Review MATLAB code for quality, performance, maintainability, and adherence to MathWorks coding standards. Uses check_matlab_code and matlab_coding_guidelines. Use when reviewing code, checking style, finding code smells,…

• Matlab Debug Code

  by @matlab

  Diagnose MATLAB errors and unexpected behavior. Breakpoints, workspace inspection, try-catch diagnostics, and common error patterns. Use when debugging functions, tracing errors, inspecting variables, or diagnosing runtime…

• Nfcore Rnastructurome Wrapper

  by @ClawBio

  Wrapper skill for running nf-core/rnastructurome — chemical-probing RNA structure analysis (SHAPE/DMS, RT-stop/MaP readout) from FASTQ to per-base reactivity, secondary-structure predictions, and 2D diagrams.

• Recombinator

  by @ClawBio

  Produce offspring genomes from parent pairs via meiotic recombination, mutation, and clinical evaluation

• Genome Match

  by @ClawBio

  Score genetic compatibility across all male-female pairings in a Genomebook generation

• Ctx

  by @ctxrs

  Use ctx as working memory for prior agent work. Before starting or continuing work in an unfamiliar area, resuming earlier work, or revisiting an investigation, search prior sessions to ground yourself in earlier context. Use…

• Docx

  by @mateaix

  Use this skill whenever the user wants to create, read, edit, or manipulate Word documents (.docx files). For CREATING new documents (report, memo, letter, résumé, contract from scratch), call the built-in tool `renderDocx`…

• Pptx

  by @mateaix

  Use this skill any time a .pptx file is involved in any way - as input, output, or both. This includes: creating slide decks, pitch decks, or presentations; reading, parsing, or extracting text from any .pptx file; editing,…

• Research Paper Writing

  by @mateaix

  Write ML papers for NeurIPS/ICML/ICLR: design→submit.

• Dspy

  by @mateaix

  DSPy: declarative LM programs, auto-optimize prompts, RAG.

• Outlines

  by @mateaix

  Outlines: structured JSON/regex/Pydantic LLM generation.

• Deai Humanize

  by @mateaix

  去AI味 / 去AI化 / 人味改写 — detect AI writing traces (AI痕迹/AI腔) with a measurable heuristic score, then rewrite text to sound human. Two tones: gzh (公众号沉稳克制) and xhs (小红书活泼碎句). humanize / de-ai / anti-ai-slop.

• Subagent Driven Development

  by @mateaix

  Execute plans via delegate_task subagents (2-stage review).

• Ideation

  by @mateaix

  Generate project ideas via creative constraints.

• Browser Cdp

  by @mateaix

  通过 Chrome DevTools Protocol (CDP) 连接已运行的浏览器，或扫描本机 CDP 端口，用于远程调试与多工具共享浏览器实例。

• Mateclaw Source Index

  by @mateaix

  将用户问题映射到 MateClaw 文档路径与源码入口，减少盲目搜索。回答'XX 功能在哪里实现'、'怎么修改 YY 逻辑'等源码定位问题。

• Plan

  by @mateaix

  Plan mode: write markdown plan to .mateclaw/plans/, no exec.

• Systematic Debugging

  by @mateaix

  4-phase root cause debugging: understand bugs before fixing.

• Node Inspect Debugger

  by @mateaix

  Debug Node.js via --inspect + Chrome DevTools Protocol CLI.

• Requesting Code Review

  by @mateaix

  Pre-commit review: security scan, quality gates, auto-fix.

• Writing Plans

  by @mateaix

  Write implementation plans: bite-sized tasks, paths, code.

• Spike

  by @mateaix

  Throwaway experiments to validate an idea before build.

• Ascii Art

  by @mateaix

  ASCII art: pyfiglet, cowsay, boxes, image-to-ascii.

• Test Driven Development

  by @mateaix

  TDD: enforce RED-GREEN-REFACTOR, tests before code.

• Python Debugpy

  by @mateaix

  Debug Python: pdb REPL + debugpy remote (DAP).

• Slides

  by @fcakyon

  Create and edit presentation slide decks (`.pptx`) with PptxGenJS, bundled layout helpers, and render/validation utilities. Use when tasks involve building a new PowerPoint deck, recreating slides from screenshots/PDFs/reference…

• Agent Browser

  by @fcakyon

  Agent-browser usage guide. Read this before running any agent-browser commands. Covers the snapshot-and-ref workflow, navigating pages, interacting with elements (click, fill, type, select), extracting text and data, taking…

• Openship Config

  by @fcakyon

  This skill should be used when the user asks to "create openship.json", "configure an OpenShip deployment", "make a repo deployable on OpenShip", or fix "openship config validate" errors.

• Codex Advisor

  by @fcakyon

  This skill should be used when the user asks for a "GPT second opinion", wants a "cross-model review", needs to "check a plan before committing", wants another view after repeated failures, or explicitly invokes "codex-advisor".

• Mongodb Connection

  by @fcakyon

  Optimize MongoDB client connection configuration (pools, timeouts, patterns) for any supported driver language. Use this skill when working/updating/reviewing on functions that instantiate or configure a MongoDB client (eg, when…

• Fable Advisor

  by @fcakyon

  This skill should be used when the user asks for a "Fable second opinion", wants to "check a plan before committing", needs another view after repeated failures, or explicitly invokes "fable-advisor".

• Review Overleaf

  by @fcakyon

  This skill should be used when user asks to "fetch overleaf review comments", "address overleaf reviews", "apply overleaf comments", "review my overleaf paper", "sync overleaf feedback to local", "what comments are on my…

• Setup

  by @fcakyon

  This skill should be used when user asks to "set up overleaf", "configure overleaf cookie", "overleaf auth failed", "overleaf 401", "overleaf session expired", "overleaf unauthorized", or needs to install or refresh their…

• Resolve Pr Comments

  by @fcakyon

  This skill should be used when user asks to "address PR comments", "resolve PR feedback", "handle review comments", "fix PR issues", "respond to PR review", or explicitly invokes "resolve-pr-comments".

• Commit Staged

  by @fcakyon

  This skill should be used when user asks to "commit these changes", "write commit message", "stage and commit", "create a commit", "commit staged files", or explicitly invokes "commit-staged".

• Adhd Output Style

  by @fcakyon

  This skill should be used when the user asks for "ADHD output", "fewer output tokens", "short numbered steps", "limited working memory formatting", or explicitly invokes "adhd-output-style".

• Create Pr

  by @fcakyon

  This skill should be used when user asks to "create a PR", "make a pull request", "open PR for this branch", "submit changes as PR", "push and create PR", or explicitly invokes "create-pr".

• Clean Gone Branches

  by @fcakyon

  This skill should be used when user asks to "clean gone branches", "remove deleted local branches", "prune branches removed from remote", or explicitly invokes "clean-gone-branches".

• Update Pr Summary

  by @fcakyon

  This skill should be used when user asks to "update PR summary", "update PR description", "rewrite PR body", "refresh PR title and body", or explicitly invokes "update-pr-summary".

• Review Pr

  by @fcakyon

  This skill should be used when user asks to "review a PR", "review pull request", "review this pr", "code review this PR", "check PR

• Vc Docs Seeker

  by @withkynam

  Search library/framework documentation via llms.txt (context7.com). Use for API docs, GitHub repository analysis, technical documentation lookup, latest library features.

• Vc Sequential Thinking

  by @withkynam

  Apply step-by-step analysis for complex problems with revision capability. Use for multi-step reasoning, hypothesis verification, adaptive planning, problem decomposition, course correction.

• Vc Audit Context

  by @withkynam

  Audit project context routing, shared-skill discoverability, and Claude/Codex wiring. Use when context docs or skill surfaces move, split, or drift.

• Vc Audit Plans

  by @withkynam

  Audit active project plan files for staleness, completion, and routing truth. Use when cleaning up plans, reconciling active work, or archiving completed artifacts.

• Vc Review Situation

  by @withkynam

  Use when you need a read-only situation review and handoff summary of current branch state, local/remote refs, worktrees, active project plans, selected-plan hints, and suggested next checks.

• Vc Scout

  by @withkynam

  Fast codebase scouting using shell search and optional parallel research agents. Use for file discovery, task context gathering, and quick scoped searches across directories.

• Vc Generate Closeout

  by @withkynam

  Generate the post-EXECUTE closeout packet for a plan or phase. Includes archive-readiness classification, drift signal scoring, commit checkpoint recommendation, and move-on next-state recommendation.

• Vc Setup

  by @withkynam

  Interactive harness setup for any project. Detects stack, scaffolds process dirs, deep-scans the codebase, populates context. Works on fresh and existing projects — always asks before reorganizing.

• Vc Publish

  by @withkynam

  Use when publishing harness improvements to the remote kit repo. Diffs managed files, shows what changed, bumps version, and pushes. Counterpart to vc-update (pull).

• Vc Update

  by @withkynam

  Pull latest agent harness improvements from the remote kit repository. Shows a dry-run diff summary, waits for confirmation, then applies updates.

• Vc Predict

  by @withkynam

  5 expert personas debate proposed changes before implementation. Catches architectural, security, performance, and UX issues early. Use before major features or risky changes.

• Best Practices

  by @MoizIbnYousaf

  Transforms vague prompts into optimized Claude Code prompts. Adds verification, specific context, constraints, and proper phasing. Invoke with /best-practices.

• Git Machete

  by @VirtusLab

  Use whenever invoking the `git machete` CLI to organize branch chains, compute fork points, run stacked rebases/merges, or manage GitHub/GitLab PR/MR chains - especially in a repo that already has a `.git/machete` file. Lists…

• Browse And Evaluate

  by @MoizIbnYousaf

  Use when exploring the ai-agent-skills catalog to find, compare, and evaluate skills before installing. Always use --fields to limit output size and --dry-run before committing to an install.

• Share A Library

  by @MoizIbnYousaf

  Use when a managed library is ready to publish to GitHub and hand to teammates as an install command. Run the GitHub publishing steps, then return the exact shareable install command.

• Code Documentation

  by @MoizIbnYousaf

  Writing effective code documentation - API docs, README files, inline comments, and technical guides. Use for documenting codebases, APIs, or writing developer guides.

• Build Workspace Docs

  by @MoizIbnYousaf

  Use when regenerating README.md and WORK_AREAS.md in a managed library workspace. Always dry-run first to preview changes.

• Guardrail Tester

  by @RyanAlberts

  Guardrail tester that checks whether the permission rules and PreToolUse hooks already set up in Claude Code, Codex, Gemini CLI, OpenCode, or Cursor stop a battery of dangerous commands, including wrapped, reordered, and…

• Claim Check

  by @RyanAlberts

  Claim checker that audits a coding agent's statements that tests pass or a build is clean against its own session transcripts: whether a matching run happened before the claim, whether it passed, and whether code changed after…

• Harness Test Drive

  by @RyanAlberts

  Test-drives coding agents (Claude Code, Codex, Gemini CLI) on tasks mined from the user's own git history: each agent gets a past commit message in a fresh copy of the repo, and the repo's own tests score how many tasks it…

• Runaway Guard

  by @RyanAlberts

  Runaway guard: a hook that stops a live Claude Code or Codex session when the agent loops on the same tool call, keeps failing, or exceeds a dollar cap. Use when the user wants a spending cap, budget limit, or cost ceiling for…

• Tool Design Checker

  by @RyanAlberts

  Grades MCP tool definitions the way a model reads them: a clear purpose, described parameters, safe annotations such as readOnlyHint, and the token size of every tool. Use when an author wants to lint, grade, or review an MCP…

• Agents Md Checker

  by @RyanAlberts

  Checks which instruction files (AGENTS.md, CLAUDE.md, GEMINI.md, Cursor rules, Copilot instructions) each coding agent loads from a repo, what gets cut or skipped, and whether the commands those files document still work. Use…

• Rules To Guards

  by @RyanAlberts

  Rule enforcer that finds which written rules in AGENTS.md, CLAUDE.md, and GEMINI.md a coding agent keeps breaking, counts every violation in recent Claude Code, Codex, Gemini CLI, and OpenCode sessions, and turns each broken…

• Regression Finder

  by @RyanAlberts

  Regression check for coding agents: shows how the agent behaved before and after each harness update, model switch, or week in the user's own Claude Code or Codex history, and finds the point where it changed. Use when the user…

• Session Waste Report

  by @RyanAlberts

  Waste report for coding-agent sessions in Claude Code, Codex, Gemini CLI, and OpenCode: finds where tokens, money, and time were wasted, and the fix for each kind of waste. Use when the user asks where tokens or money went or…

• Sandbox Check

  by @RyanAlberts

  Sandbox audit that probes, from inside a live coding-agent session, what the agent can really reach: secret files it can open, secret-like environment variables, files that git, the shell, the editor, or the harness later run…

• Reddit Insights

  by @lignertys

  Search Reddit posts by meaning via the reddapi.dev index.

• Reddapi

  by @lignertys

  The original reddapi.dev Reddit search skill (vector search, semantic search, trends, subreddit discovery), no Reddit OAuth or app registration needed. This is the same engine now packaged as reddit-research with added…

• Reddit Search Api

  by @lignertys

  Pure API reference for reddapi.dev - authentication, all endpoints (vector search, semantic search, trends, subreddit lookup), request parameters, response schemas, and error codes, with no research-workflow framing. Use when…

• Reddit Leads

  by @lignertys

  Discover B2B leads from Reddit using AI-powered lead scoring via reddapi.dev Leads API. Finds high-intent signals, scores them 0-100, and classifies by lead type (pain_point, solution_request, complaint, feature_request,…

• Sketchforge Mcp Skill

  by @Formsmith746

  Control a live local SketchForge editor through its MCP server. Use when Codex needs to list currently open SketchForge editor tabs, target a tab by editorNumber/projectName, read the current scene, list or select objects,…